INTRODUCTION
BACKGROUND TO THE STUDY
One of the major challenges of the last 50 years is antimicrobial resistance, an additional 30 years from now, and the world would be deemed to be in the post antibiotic era. Antimicrobial resistance is a menace and microorganisms regardless of their origin, specie, group are assiduously taking advantage of all of the available means to acquire resistance to all of the available antimicrobials.
Now, virtually every microbial isolate has acquired one or more forms of antimicrobial resistance and the isolates of wound (22%), air (43%), inanimate surfaces (55%), gastrointestinal tract (28%), stool (32%) are constantly involved in this even those isolates of water are presenting resistance results and the most common isolates between this sources are Escherichia coli (45%), Staphylococcus aureus (62%), Klebsiella pneumonia (33%), Pseudomonas aeruginosa (18%), Bacillus sp. (48%) with varying track records of resistance. Research has detailed the cost of treating microbiological infectious diseases and has observed failure in treatment due to poor performance or effectiveness of antimicrobials in the therapy of common microbiological infections as in typhoid fever, gastroenteritis, skin infections and other medical complications (Nkansah et al., 2010; Dada et al., 2011; Akple et al., 2011; Ukpong et al., 2013; Adedeji et al., 2017; Eboh et al., 2017; Onuigbo et al., 2017; Omotoso et al., 2018; Kilungo et al., 2018; Kurwadkar et al., 2019; Onwa et al., 2019; Ayandele et al., 2019; Akinnifesi and Akinneye, 2019; Nwinyi et al., 2020; Gebresilasie et al., 2021).